HIV treatment pause study tests antibody cocktail plus immune booster

NCT ID NCT05245292

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study tested whether a combination of two long-acting antibodies (3BNC117-LS and 10-1074-LS) plus an immune-boosting drug (N-803) can safely control HIV in people who temporarily stop their regular antiretroviral therapy. 28 adults with well-controlled HIV took part. The goal was to see if the treatment could delay or prevent the virus from rebounding without needing daily pills.

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Contacts and locations

Locations

  • Perelman School of Medicine University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • The Rockefeller University

    New York, New York, 10065, United States

  • Weill Cornell Medicine, Cornell Clinical Trials Unit

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.