Can a simple steroid boost recovery after hip replacement?
NCT ID NCT07378215
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a single dose of the anti-inflammatory drug dexamethasone, given during hip replacement surgery, can help patients feel better and recover faster. About 224 adults aged 60 and older having a hip replacement will receive either a low or moderate dose of the drug. Researchers will track their quality of life and recovery for up to three months after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 224 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * aged 60 years or older; * scheduled for elective total hip arthroplasty; * procedure under spinal anaesthesia. Exclusion Criteria: * hip revision surgery (reoperation); * bilateral total hip arthroplasty during the same procedure; * known hypersensitivity to dexamethasone or other corticosteroids; * chronic systemic use of corticosteroids, defined as daily corticosteroid therapy for \> 4 weeks within the last 3 months, with anticipated need for a perioperative stress dose of corticosteroids; * active gastric of intestinal ulcers; * lack of informed consent or inability to give informed consent; * urgent, non-elective surgery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ziekenhuis Oost-Limburg
NOT_YET_RECRUITINGGenk, Limburg, 3600, Belgium
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Ziekenhuis Oost-Limburg
RECRUITINGGenk, Belgium
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