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Heated chemo during surgery: does it slow down gut recovery?

NCT ID NCT07353177

Knowledge-focused Sponsor: Peking University People's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks back at 193 people with stomach, appendix, or colon cancer who had surgery with or without heated chemotherapy (HIPEC). Researchers want to see if HIPEC affects how quickly the bowels start working again after surgery and whether it leads to more complications. The goal is to better understand recovery and improve care for future patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Heated chemotherapy (cisplatin, 5-fluorouracil, or raltitrexed) given directly into the abdomen during surgery
What this could lead to
If successful, this could help doctors understand whether heated chemotherapy affects bowel recovery after surgery, potentially improving post-surgery care.
What could go wrong
This is a small, single-center retrospective study, not a controlled trial. Results may not apply to all patients, and the study cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 193 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Involving patients with gastric cancer, appendiceal mucinous neoplasm, or colon cancer who underwent gastrectomy or hemicolectomy surgery with or without HIPEC between January 2017 and December 2023.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinical diagnosis of gastric, appendiceal, or colon malignant tumors of stage T4b or peritoneal metastases; * Karnofsky performance status (KPS) score \>50; * Life expectancy \>3 months; * Peripheral white blood cell count ≥3,500/mm3 and platelet count ≥80,000/mm3; * Acceptable liver, renal, cardiovascular, pulmonary, and coagulation function, and other major organ functions were able to endure a major operation. Exclusion Criteria: * Emergency surgery due to intestinal obstruction or perforation; * A history of inflammatory bowel disease (IBD); * Two or more independent surgical procedures on the gastrointestinal tract; * Postoperative enema.

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Conditions

The condition(s) this trial relates to.

colon carcinoma digestive system cancer gastric cancer mucinous adenocarcinoma of the appendix

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adhesion prevention Bowel functions Gastro-intestinal cancer HIPEC

Contacts and locations

Locations

  • Peking university people's hospital

    Beijing, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.