Could short bursts of exercise ease stubborn shoulder pain?
NCT ID NCT07275164
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether high-intensity interval training (HIIT) is a feasible and acceptable option for people with long-term shoulder pain, such as rotator cuff issues or frozen shoulder. Researchers will enroll 15 people with shoulder pain and 15 without, measuring inflammation, blood sugar, and pain sensitivity. Participants with shoulder pain will do one 20-minute HIIT session on a stationary bike. The goal is to see if this approach is practical and safe, and whether it might reduce inflammation linked to persistent pain.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- High-intensity interval training (HIIT) on a cycle ergometer
- What this could lead to
- If successful, this could pave the way for larger studies exploring HIIT as a treatment for chronic shoulder pain by targeting inflammation and nervous system function.
- What could go wrong
- This is a very small feasibility study with only 15 participants, so results may not apply broadly. It is not designed to prove effectiveness, only to see if the approach is practical and acceptable.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Shoulder pain group * Shoulder pain \> 3 months * Diagnosis of rotator cuff related shoulder pain or frozen shoulder * Understanding Dutch in speaking and writing. Control group o Understanding Dutch in speaking and writing Exclusion Criteria: Shoulder pain group * \<18 years * Shoulder surgery or trauma in past year * Neurological, cancer, or neuromuscular disease * Osteoarthritis, cervical or AC joint pathology * Heavy physical exertion \<48h before testing Control group * \<18 years * recent or recurrent neck/shoulder pain * systemic or neurological disease * psychiatric disorders * pregnancy/breastfeeding * pain medication \<48h before test
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Universiteit Antwerpen
RECRUITINGWilrijk, 2610, Belgium
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Other studies related to the condition(s) this trial covers.
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