Blood test may replace scans for heart attack staging
NCT ID NCT07163988
First seen Jun 27, 2026 · Last updated Sep 17, 2026 · Updated 2 times
Summary
This study looked at whether a high-sensitivity blood test for troponin I can accurately determine the stage of a heart attack. Researchers analyzed data from 312 patients across multiple hospitals. The goal is to provide a faster, simpler way to classify heart attack severity without relying on imaging.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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312 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of individuals aged 18 to 80 who have been diagnosed with acute ST-elevation myocardial infarction (STEMI) and are scheduled for emergency percutaneous coronary intervention (PCI).
- Ages
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18 to 79 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-79 years * Index STEMI * Coronary angiogram with PCI to occur irrespective of the onset of the symptoms. * Ability to provide informed consent for themselves Exclusion Criteria: * History of prior myocardial infarction, * Cardiogenic shock, * Patients who present with current cardiac arrest * Any contraindication to cardiac CMR (claustrophobia, pacemaker or cardiac defibrillator, known allergy to gadolinium), * Presence of permanent atrial fibrillation, * Unconscious patient, * Severe renal insufficiency (creatinine clearance ≤ 30 ml/min/m2 or renal replacement therapy), * Women who are pregnant or breastfeeding. Women of reproductive potential must have a negative pregnancy test.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical Imaging Research Institute
Indianapolis, Indiana, 46202, United States
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Other studies related to the condition(s) this trial covers.
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