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Heart pump could protect patients during risky stent procedures

NCT ID NCT05003817

First seen Feb 21, 2026 · Last updated Jun 20, 2026 · Updated 19 times

Summary

This study tests a temporary heart pump in 300 high-risk patients with severe coronary artery disease and weak heart muscle. The pump supports the heart during stenting to prevent failure. Researchers want to see if it reduces death, stroke, or heart-related hospital stays.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Guy's and St Thomas' NHS Foundation Trust

    London, SE1 7EH, United Kingdom

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

percutaneous left ventricular unloading device (a temporary heart pump)

What this could lead to

If successful, this could provide a safer way to perform stenting in high-risk patients, reducing serious complications like heart failure or death.

What could go wrong

The device itself carries risks like bleeding or leg artery damage, and it is expensive. This is a Phase 3 trial, so results are not yet confirmed.

Conditions

The condition(s) this trial relates to.

coronary artery disorder myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.