Exercise boosts strength and mood in seniors with sarcopenia?
NCT ID NCT07399301
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether high-intensity functional training can improve physical performance and mental health in elderly people with sarcopenia (age-related muscle loss). Sixty participants aged 60-70 will be split into two groups: one doing intense exercises 3 times a week for 10 weeks, and the other doing sham exercises. The main goal is to see if the training improves balance, strength, and walking speed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- High-intensity functional training exercises
- What this could lead to
- If it works, this could point toward a simple exercise program to help elderly people with sarcopenia move better and feel better.
- What could go wrong
- This is a small, early-stage trial with only 60 participants. The sham exercise group may also improve, making it hard to see a clear benefit. Results may not apply to all elderly people.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: INCLUSION CRITERIA: 1. Old individuals who will be found to have sarcopenia as defined according to European Working Group on Sarcopenia in Older People (EWGSOP2) 2019 criteria, The EWGSOP2 defines sarcopenia as a muscle disease characterized by progressive and generalized loss of skeletal muscle mass and function. Diagnosis requires sequential assessment of three components * Low Muscle Strength: The primary criterion. Measured by: * Handgrip strength: Cut-offs are \<27 kg for men and \<16 kg for women using a dynamometer. * Chair Stand Test: ≥15 seconds for five rises indicates weakness. * Low Muscle Quantity or Quality: Assessed via: o calf circumference (≤34 cm men, ≤33 cm women). * Poor Physical Performance: Indicates severe sarcopenia. Tests include: * Gait speed: ≤0.8 m/s over 4 meters. * Short Physical Performance Battery (SPPB): ≤8 points. * Timed Up-and-Go (TUG): ≥20 seconds. 2. Age from 60 to 70 years old. 3. Old individuals who will be found to have mild depression. Exclusion Criteria: 1. Neurological disorders. 2. Vestibular or balance disorders. 3. Uncontrolled hypertension or heart diseases. 4. Recent surgeries or fractures. 5. Any psychological disorders. 6. Severe renal failure (glomerular filtration rate \< 30 mL/min). 7. moderate to severe liver failure. 8. The patients cannot follow instructions.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Physical Therapy
Giza, 12613, Egypt