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Laser light could ease knee arthritis without drugs or surgery

NCT ID NCT07661407

Symptom relief Sponsor: University of Rzeszow Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study investigates whether adding High-Intensity Laser Therapy (HILT) to standard physiotherapy helps people with mild-to-moderate knee osteoarthritis. Seventy-two participants will receive either real or sham laser sessions alongside exercise-based physiotherapy. Researchers will measure pain, knee function, strength, and quality of life over eight weeks to see if the laser provides extra relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-Intensity Laser Therapy (HILT)
What this could lead to
If effective, HILT could offer a non-drug, non-surgical option to reduce pain and improve mobility in people with knee osteoarthritis.
What could go wrong
This is a small, early-stage trial with 72 participants. The laser may not provide more benefit than placebo, and results may not apply to severe cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Radiographically confirmed knee osteoarthritis * Mild-to-moderate disease severity * Pain ≥4 on VAS for at least 3 months * Ability to participate in physiotherapy * Informed consent Exclusion Criteria: * Advanced OA requiring surgery * Previous knee arthroplasty * Knee instability * Acute inflammation * Neurological disorders affecting gait * Neuropathies or myopathies * Active inflammatory arthritis * Recent lower-limb injury (\<6 months) * Intra-articular injections within 3 months * Cancer, pregnancy, epilepsy * Electronic implants or pacemaker * Active local infection

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis (knee oa)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.