New study aims to unravel clotting mysteries in rare viral disease
NCT ID NCT06944275
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at why some people with a rare virus called hantavirus develop serious bleeding and kidney failure. Researchers will study blood samples from 62 hospitalized patients in Slovenia to understand how clotting goes wrong. The goal is to better predict who is at risk and find new ways to treat the disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 62 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
May 2026
An estimate. Start dates often move.
- Expected to finish
-
Aug 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients will be recruited from the University Medical Centre Ljubljana. Suspected cases of HFRS will be identified based on a clinical case definition of presence of fever and one of the following: acute kidney injury (AKI), thrombocytopenia, bleeding, or epidemiological risk. Cases will be confirmed for inclusion in the study following laboratory confirmation of hantavirus infection using serological methods for antibody detection or reverse transcription polymerase chain reaction (RT-PCR) to detect hantavirus genetic material in the blood.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18 or older, including pregnant women * Laboratory-confirmed HFRS (serology and/or RT-PCR) * Willing and able to provide informed consent Exclusion Criteria: * Patients under 18 years of age * Co-infections with other pathogens * Pre-existing coagulation disorders * Use of anticoagulant medication * Inability or refusal to provide consent
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Haemorrhagic fever with renal syndrome are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.