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Nature's mouthwash: could tea tree oil and thyme tame gum disease?

NCT ID NCT06904742

Disease control Sponsor: Altinbas University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial tests whether herbal mouthwashes containing tea tree oil, thyme hydrosol, or essential oils can reduce the plaque and gum inflammation seen in gingivitis. About 52 adults with gingivitis will use one of these mouthwashes or a placebo twice daily for three months, alongside standard non-surgical gum treatment. Researchers will measure changes in plaque, gum bleeding, and pocket depths to see if these natural rinses offer extra benefit.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Herbal mouthwashes (tea tree oil, thyme hydrosol, and essential oil) used as an adjunct to non-surgical periodontal therapy
What this could lead to
If effective, these herbal mouthwashes could offer a natural, accessible way to improve gum health and prevent gingivitis from progressing to more serious periodontal disease.
What could go wrong
This is a small, early-stage trial with only 52 participants, so results may not apply broadly. The mouthwashes may not outperform the placebo or standard care, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

52 people

The number who actually took part.

Started

Feb 2025

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * According to EFP in 2017, gingivitis patients with a PPD ≤3 mm, BOP in the whole mouth ≥ % 10 and no radiological bone loss * Having ≥ 20 teeth * Male or female ≥ 18 years old * Systemically healthy patients Exclusion Criteria: * Using of any antioxidant or antimicrobial agent in the last 6 months •. Smoking * Pregnancy * Alcoholism

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Conditions

The condition(s) this trial relates to.

gingivitis periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontal diseases

Contacts and locations

Locations

  • Altinbas University

    Istanbul, Bakirkoy, 34149, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.