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Can HER2 patterns predict breast cancer drug success?

NCT ID NCT06551220

First seen May 23, 2026 · Last updated May 23, 2026

Summary

This study looks at how differences in HER2 levels and location across tumors impact the effectiveness of the drug trastuzumab deruxtecan in people with metastatic breast cancer. Researchers will follow 800 participants to see if these variations affect how long the cancer stays under control. The goal is to better understand who benefits most from this treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Cancer Hospital of Inner Mongolia Medical University

    RECRUITING

    Hohhot, Inner Mongolia, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cancer Hospital of Shantou University Medical College

    RECRUITING

    Shantou, Guangdong, 515041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Changde Hospital, Xiangya School of Medicine, Central South University

    RECRUITING

    Changde, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dana-Farber Cancer Institute, Harvard Medical School

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Email: •••••@•••••

  • Fujian Cancer Hospital, Fujian Medical University

    RECRUITING

    Fuzhou, Fujian, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guangdong Provincial Hospital of Chinese Medicine

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University

    RECRUITING

    Changsha, Hunan, 410013, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Cancer Center Shenzhen Hospital

    RECRUITING

    Shenzhen, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shenzhen People's Hospital

    RECRUITING

    Shenzhen, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The 10th Affiliated Hospital of Southern Medical University

    RECRUITING

    Dongguan, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Affiliated Cancer Hospital, Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Affiliated Panyu Central Hospital, Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, 511400, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Fifth Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Zhuhai, Guangdong, 519000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Guangzhou University of Chinese Medicine

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Nanjing Medical University

    RECRUITING

    Nanjing, Jiangsu, 210029, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital, Hengyang Medical School, University of South China

    RECRUITING

    Hengyang, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First People's Hospital of Foshan

    RECRUITING

    Foshan, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital, Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, China

    Contact Email: •••••@•••••

  • The Second Xiangya Hospital of Central South University

    RECRUITING

    Changsha, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Sixth Affiliated Hospital, School of Medicine, South China University of Technology.

    RECRUITING

    Foshan, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xinhua Hospital Afliated to Shanghai Jiaotong University

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yale Cancer Center

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact Email: •••••@•••••

  • Yuebei People's Hospital of Shantou University

    RECRUITING

    Shaoguan, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhongshan City People's Hospital

    RECRUITING

    Zhongshan, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.