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Blood test finds hidden targets: new hope for HER2-Negative breast cancer patients

NCT ID NCT01975142

First seen Dec 09, 2025 · Last updated May 18, 2026 · Updated 16 times

Summary

This study looked at 155 people with metastatic breast cancer whose original tumors were HER2-negative. Researchers checked their blood for cancer cells that had extra HER2 genes. If found, participants received the drug T-DM1. The goal was to see if these hidden HER2-positive cells could predict who would respond to treatment, offering a new option for patients who otherwise would not qualify for this therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre Catherine de Sienne

    Vandœuvre-lès-Nancy, 54519, France

  • Centre Oscar Lambret

    Lille, 59020, France

  • Centre Val d'Aurelle - P. Lamarque

    Montpellier, 34298, France

  • Chu Saint-Louis

    Paris, 75475, France

  • Chu de Limoges

    Limoges, 87042, France

  • Clinique Victor Hugo

    Le Mans, 72000, France

  • Institut Curie

    Paris, 75005, France

  • Institut Curie - Hôpital René HUGENIN

    Saint-Cloud, SAINT-CLOUD, France

  • Institut de Cancérologie HARTMANN

    Levallois-Perret, 92309, France

  • Institut de Cancérologie de Lorraine

    Vandœuvre-lès-Nancy, 54519, France

Conditions

Explore the condition pages connected to this study.