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Can a simple heparin shot save stroke Patients' arteries?

NCT ID NCT07162064

Disease control Sponsor: Xiang Luo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving heparin (a blood thinner) during brain angiography can prevent the radial artery in the wrist from becoming blocked afterward. The trial involved 440 acute stroke patients and compared heparin to a placebo. The goal was to see if heparin reduces artery blockage without causing dangerous bleeding.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Heparin
What this could lead to
If successful, this could establish a safe way to prevent radial artery blockage after brain angiography in stroke patients, preserving future access for procedures.
What could go wrong
This is a completed Phase 3 trial, but the results are not yet published. Heparin may increase bleeding risk in stroke patients, and the benefit may not outweigh the risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

440 people

The number who actually took part.

Started

Aug 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥18 years 2. Acute ischemic stroke onset within 7 days (inclusive) 3. Patients undergoing cerebral angiography via transradial approach 4. Participant or legal representative capable of providing informed consent Exclusion Criteria: 1. Current anticoagulation therapy prior to procedure 2. Positive modified Allen's test result 3. History of coronary artery bypass grafting(CABG) with missing right radial artery graft 4. Severe forearm deformities (skin/musculoskeletal) or failed radial artery sheath placement 5. Suspected/confirmed pregnancy or lactation 6. Acute ischemic stroke with hemorrhagic transformation 7. Active systemic bleeding 8. Renal insufficiency (eGFR \<30 mL/min or serum creatinine \>200 μmol/L) 9. Investigator-determined ineligibility for trial participation

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute ischemic stroke

Contacts and locations

Locations

  • Tongji Hospital

    Wuhan, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.