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2 million people to share DNA in massive health study

NCT ID NCT06057181

Knowledge-focused Sponsor: Helix, Inc Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to build a research network of up to 2 million adults to collect genetic and health information. Participants will provide a DNA sample for exome sequencing, and researchers will analyze the data to find genetic markers linked to diseases. The goal is to improve understanding of how genes affect health and to speed up the use of genomics in medical care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could create a massive database to help researchers discover genetic links to diseases, leading to better risk prediction and personalized medicine.
What could go wrong
This is an observational study, not a treatment trial. It may take years to yield actionable results, and findings may not directly benefit participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,000,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2021

Expected to finish

Sep 2036

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study will recruit the general population from the surrounding areas of the HRN Member Sites. This may include patients within a health system of the Site or community members in the surrounding area of Sites.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years and older * Willing and able to comply with all aspects of the protocol Exclusion Criteria: * History of allogenic bone marrow transplant * History of allogenic stem cell transplant * Anything that would place the individual at increased risk or preclude an individual's: 1) full compliance with study requirements; or 2) completion of the study based on the assessment from local consenting and enrolling Investigators.

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Conditions

The condition(s) this trial relates to.

hereditary disease inherited disease susceptibility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Genetic predisposition to disease Genetics disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    14 sites. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Cone Health (Gene Connect)

    RECRUITING

    Burlington, North Carolina, 27401, United States

  • HealthPartners (myGenetics)

    RECRUITING

    Bloomington, Minnesota, 55425, United States

  • Medical University of South Carolina (In Our DNA SC)

    RECRUITING

    Charleston, South Carolina, 29425, United States

  • Memorial Hermann Health System (genoME)

    RECRUITING

    Houston, Texas, 77030, United States

  • Nebraska Medicine - University of Nebraska Medical Center (Genetic Insights Project)

    RECRUITING

    Omaha, Nebraska, 68198, United States

  • Parkview Health (DNA Insights)

    RECRUITING

    Fort Wayne, Indiana, 46845, United States

  • Renown Health (Healthy Nevada Project)

    RECRUITING

    Reno, Nevada, 89502, United States

  • Rochester Regional Health (GenoWell)

    RECRUITING

    Rochester, New York, 14621, United States

  • Sanford Health (Imagine You)

    RECRUITING

    Sioux Falls, South Dakota, 57105, United States

    Contact Email: •••••@•••••

  • St. Luke's University Health Network (DNAanswers)

    RECRUITING

    Bethlehem, Pennsylvania, 18015, United States

  • The Ohio State University (Genomic Health)

    RECRUITING

    Columbus, Ohio, 43210, United States

  • TriHealth (DNA Discovery)

    RECRUITING

    Cincinnati, Ohio, 45202, United States

  • WakeMed (PreciselyYou)

    RECRUITING

    Raleigh, North Carolina, 27610, United States

  • WellSpan Health (The Gene Health Project)

    RECRUITING

    York, Pennsylvania, 17403, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.