Sweat it out: army study tests overdressing for heat adaptation

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female, age 18-45 * Females must be premenopausal * Body mass index 18.5-30.0 kg m-2 * In good health as determined by the Office of Medical Support \& Oversight (OMSO) General Medical Clearance * Performs aerobic exercise at least 2 times per week and capable of running 2 miles in under 16:00 (8 minute mile pace) * Willing to abstain from exercise and alcoholic beverages for 24 hours before each study visit. * Willing to abstain from caffeine for 12 hours prior to all study visits. * Willing to abstain from food for 2 hours prior to all study visits. * Willing to abstain from nicotine/tobacco for at least 8 hours prior to all study visits. * Have supervisor approval if permanent party military or a federal employee at U.S. Army Natick Soldier System Center Exclusion Criteria: * Females who are pregnant or planning to become pregnant during the study * Taking dietary supplements, prescriptions, or over the counter medication, other than a contraceptive (unless approved by OMSO \& PI) * Abnormal blood count during OMSO medical screening (For example: hemoglobin (Hb) outside of the typical normal values reported by LabCorp in accordance with OMSO (Normal \[Hb\] Males = 12.6-17.7 g/dL; Females = 11.1-15.9 g/dL) or hematocrit (Hct) outside of the normal ranges (Normal Hct Males = 37.5-51.0%; Females = 34.0-46.6%) levels, presence of abnormal blood chemicals (hemoglobin S or sickle cell traits) * Any history of pulmonary or cardiovascular disease * Any history of asthma * Current or recent respiratory tract or sinus infections (\< 1 month prior) * History of heat intolerance or orthostatic intolerance * Diagnosed and/or treated for fluid/electrolyte imbalance within the last 30 days * History of obstructive disease of the gastrointestinal tract including (but not limited to) diverticulosis, diverticulitis and inflammatory bowel disease, peptic ulcer disease, Crohn's disease, ulcerative colitis. * Scheduled MRI during testing * Allergies to adhesives (e.g., medical tape).