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Army researchers hunt for heat stroke warning signs in soldiers

NCT ID NCT06907225

Knowledge-focused Sponsor: United States Army Research Institute of Environmental Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study observes 150 military personnel during high-risk training events like ruck marches and timed runs to understand heat stress. Researchers will collect blood, urine, and body temperature data before, during, and after exercise. The goal is to find biomarkers that could predict heat stroke risk and guide recovery and return-to-duty decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could identify early warning signs for heat stroke and help improve recovery and return-to-duty decisions for soldiers.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear biomarkers, and results may not apply to non-military populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The sample population included in this investigation will be that of Soldiers undergoing high-risk training events in military training. There are no gender, race, or ethnicity limitations.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals (to include cis- and transgender males and females and nonbinary) 18 years of age or greater * Current military service (active, Reserve, or National Guard) * Currently participating in training Exclusion Criteria: * Females who are pregnant * Any individual currently on a physical profile that restricts running or foot marching * History of obstructive disease of the gastrointestinal tract including (but not limited to) diverticulosis, diverticulitis and inflammatory bowel disease, peptic ulcer disease, Crohn's disease, ulcerative colitis. * Scheduled MRI within 2 weeks after core temp pill ingestion * Known allergies to skin adhesive * Blood donation in the past 8 weeks

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Conditions

The condition(s) this trial relates to.

exercise-induced malignant hyperthermia Heat Stress Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Thermoregulation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Field Study

    NOT_YET_RECRUITING

    Fort Jackson, South Carolina, 29207, United States

  • Fort Novosel

    RECRUITING

    Fort Novosel, Alabama, 36362, United States

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