New study aims to spot heart transplant rejection without a biopsy
NCT ID NCT06774365
First seen May 24, 2026 · Last updated Jun 19, 2026 · Updated 6 times
Summary
This study looks at 683 heart transplant patients to see if advanced heart scans (CMR) and blood tests can detect antibody-mediated rejection, a common complication. Participants must be stable and at least one year post-transplant. The goal is to find non-invasive ways to diagnose rejection earlier and more accurately.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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ASST Grande Ospedale Metropolitano Niguarda
RECRUITINGMilan, Milano, 20162, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Azienda Ospedaliera Universitaria Consorziale Policlinico di Bari
NOT_YET_RECRUITINGBari, Bari, 70120, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Azienda Ospedaliera dei Colli
RECRUITINGNaples, Napoli, 80131, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IRCCS Azienda Ospedaliero-Universitaria di Bologna
RECRUITINGBologna, Bologna, 40138, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to better, non-invasive ways to detect rejection in heart transplant patients, reducing the need for biopsies.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly improve outcomes. Results may not change current practices if imaging or biomarkers prove unreliable.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.