Massive trial probes heart risks of popular Weight-Loss pill

NCT ID NCT06098079

Ongoing Disease control Sponsor: Currax Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study aims to find out if a prescription weight loss drug (Contrave/Mysimba) increases the risk of serious heart problems like heart attacks or strokes. It will enroll 8,600 overweight or obese adults who already have a higher risk for heart disease. Participants will be randomly assigned to receive either the real medication or a placebo (sugar pill), and both groups will also receive advice on diet and exercise.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Locations

ABMED Clinical Research

Cape Coral, Florida, 33914, United States
AMR - El Dorado

El Dorado, Kansas, 67042, United States
AMR Mobile

Mobile, Alabama, 36608, United States
AMR New Orleans

New Orleans, Louisiana, 70119, United States
AMR Norfolk

Norfolk, Virginia, 23502, United States
AMR Wichita East

Wichita, Kansas, 67207, United States
AMR Wichita West

Wichita, Kansas, 67205, United States
Accel Research Sites (ARSN) - Neurostudies

Decatur, Georgia, 30030, United States
Accel Research Sites Network

Birmingham, Alabama, 35216, United States
Accel Research Sites Network - Edgewater

Edgewater, Florida, 32132, United States
ActivMed Practices and Research

Portsmouth, New Hampshire, 03801, United States
Activmed Practices and Research, Inc

Methuen, Massachusetts, 01844, United States
Advanced Cardiovascular Specialists/NextStage Clinical Research

Beaumont, Texas, 77702, United States
Advanced Clinical Research

Miami, Florida, 33156, United States
Advanced Clinical Research Atlanta

Atlanta, Georgia, 30309, United States
All-American Orthopedics-NextStage Clinical Research

Houston, Texas, 77058, United States
Altus Research

Lake Worth, Florida, 33461, United States
Avacare

Las Vegas, Nevada, 89102, United States
Axces Research Group

Santa Fe, New Mexico, 87505, United States
Best Choice Medical and Research Services

Pembroke Pines, Florida, 33024, United States
Biscayne Clinical Research Inc

North Miami, Florida, 33169, United States
Bolanos Clnical Research

Pembroke Pines, Florida, 33028, United States
Cardiovascular Consultants/NextStage Clinical Research

Glendale, Arizona, 85306, United States
Century Research

Miami, Florida, 33173, United States
Charlottesville Medical Research

Charlottesville, Virginia, 22911, United States
Chemidox Clinical Trials Inc.

Lancaster, California, 93534, United States
Clay Platte Family Medicine

Kansas City, Missouri, 64151, United States
Clincept Clinical Research

Columbus, Georgia, 31904, United States
Coastal Carolina Research Center

North Charleston, South Carolina, 29405, United States
Conveinent Medical Research

Hialeah, Florida, 33013, United States
Cordova Research Institute

Sweetwater, Florida, 33182, United States
Cullman Clinical Trials

Cullman, Alabama, 35055, United States
D&H Doral Research Center

Doral, Florida, 33122, United States
D&H Pompano Research Center, LLC

Margate, Florida, 33063, United States
D&H Tamarac Research Center, LLC

Tamarac, Florida, 33321, United States
Dearborn Cardiology

Dearborn, Michigan, 48126, United States
Delray Physician Center

Delray Beach, Florida, 33445, United States
Desert Clinical Research

Mesa, Arizona, 85213, United States
Entrust Clinical Research

Miami, Florida, 33176, United States
Evergreen Surgical

Eau Claire, Wisconsin, 54701, United States
Fiel Family & Sports Medicine CCT Research

Tempe, Arizona, 85283, United States
G+C Research Group

Hialeah, Florida, 33010, United States
HDH Research

Houston, Texas, 77022, United States
Hatboro Medical Associates/Avacare Research

Horsham, Pennsylvania, 19044, United States
Healix Clinical Research

New Smyrna Beach, Florida, 32168, United States
IMRC At Palmetto Bay

Palmetto Bay, Florida, 33157, United States
IMRC Fort Lauderdale

Fort Lauderdale, Florida, 33316, United States
ITB Research

Miami, Florida, 33173, United States
Ilumina Medical Research

Kissimmee, Florida, 34744, United States
Indiana Medical Research Institute

Merriville, Indiana, 46410, United States
Innovia Research Center

Miramar, Florida, 33027, United States
JAELEX Research

Round Lake Beach, Illinois, 60073, United States
JY Research Institute

Cutler Bay, Florida, 33189, United States
Janus Clinical Research

Miami, Florida, 33186, United States
LMG Research

Coral Gables, Florida, 33134, United States
Las Vegas Clinical Trials

North Las Vegas, Nevada, 89119, United States
Long Beach Clinical Trials

Long Beach, California, 90806, United States
Medical Research Center Westchester

Miami, Florida, 33165, United States
Mercado Medical Practice/CCT Research

Philadelphia, Pennsylvania, 19111, United States
Meridian Clinical Research - Velocity

Omaha, Nebraska, 68134, United States
Miami Beach Clinical Research

Miami Beach, Florida, 33141, United States
Midwest Regional Health Services

Omaha, Nebraska, 68144, United States
National Institute of Clinical Research, Inc.

Pomona, California, 91768, United States
New Horizons Research

Palmetto Bay, Florida, 33176, United States
NexGen Research

Lima, Ohio, 45801, United States
NextStage Clinical Research - Tulsa

Tulsa, Oklahoma, 74136, United States
NextStage Clinical Research-Chicago

Glen Ellyn, Illinois, 60137, United States
NextStage Clinical Research-Lubbock/SWAT Surgical Associates-NextStage Clinical Research

Lubbock, Texas, 79410, United States
NextStage Clinical Research-Port Arthur/Gulf Coast Cardiology

Port Arthur, Texas, 77642, United States
Olympus Clinical Research

Sugarland, Texas, 77479, United States
Optimal Research, LLC. - Austin

Austin, Texas, 78705, United States
Optimal Research, LLC. - Melbourne

Melbourne, Florida, 32934, United States
Praveen K Gupta, MD/Avacare

Rockville, Maryland, 20852, United States
Providere Research

West Covina, California, 91790, United States
Qway Research

Hialeah, Florida, 33010, United States
Regenerative Orthopedics and Sports Medicine- NextStage Clinical Research

North Bethesda, Maryland, 20852, United States
Santa Rosa Urgent Care Primary Care/CCT Research

Las Vegas, Nevada, 89119, United States
Southwest General Healthcare Center

Fort Myers, Florida, 33907, United States
St. Louis Medical Professionals/CCT Research

St Louis, Missouri, 63119, United States
Sun City Research

Glendale, Arizona, 85304, United States
Synexus Clinical Research US, Inc. - New York

New York, New York, 10017, United States
Synexus Clinical Research US, Inc. - The Villages

The Villages, Florida, 32162, United States
Synexus Clinical Research US; Inc.

Tucson, Arizona, 85741, United States
Synexus Clinical Research US; Inc.

San Antonio, Texas, 78229, United States
TrialMed Birmingham (DRS)

Birmingham, Alabama, 35211, United States
Valley Vitality Ventures

Manteca, California, 95350, United States
Velocity Clinical Research

Chula Vista, California, 91911, United States
Velocity Clinical Research

Los Angeles, California, 90057, United States
Velocity Clinical Research

Valparaiso, Indiana, 46383, United States
Velocity Clinical Research

Sioux City, Iowa, 51106, United States
Velocity Clinical Research

Baton Rouge, Louisiana, 70809, United States
Velocity Clinical Research

Covington, Louisiana, 70433, United States
Velocity Clinical Research

Lafayette, Louisiana, 70508, United States
Velocity Clinical Research

Slidell, Louisiana, 70458, United States
Velocity Clinical Research

Gulfport, Mississippi, 39503, United States
Velocity Clinical Research

Lincoln, Nebraska, 68510, United States
Velocity Clinical Research

Albuquerque, New Mexico, 87107, United States
Velocity Clinical Research

Binghamton, New York, 13905, United States
Velocity Clinical Research

Vestal, New York, 13850, United States
Velocity Clinical Research

Beachwood, Ohio, 44122, United States
Velocity Clinical Research

Cincinnati, Ohio, 45246, United States
Velocity Clinical Research

Anderson, South Carolina, 29621, United States
Velocity Clinical Research

Charleston, South Carolina, 29414, United States
Velocity Clinical Research

Columbia, South Carolina, 29204, United States
Velocity Clinical Research

Gaffney, South Carolina, 29340, United States
Velocity Clinical Research

Greenville, South Carolina, 29615, United States
Velocity Clinical Research

Austin, Texas, 78759, United States
Velocity Clinical Research (New Smyrna Beach)

Edgewater, Florida, 32132, United States
Velocity Clinical Research (Providence)

East Greenwich, Rhode Island, 02818, United States
Velocity Clinical Research (St. Louis)

St Louis, Missouri, 63131, United States
Velocity Clinical Research at Coastal Heart Medical Group

Santa Ana, California, 92704, United States
Velocity Clinical Research at Pioneer Heart Institute

Lincoln, Nebraska, 68506, United States
Velocity Clinical Research of Santa Ana

Santa Ana, California, 92704, United States
Velocity Clinical Research, Abilene

Abilene, Texas, 79606, United States
Velocity Clinical Research, Cincinnati

Cincinnati, Ohio, 45242, United States
Velocity Clinical Research, Denver

Englewood, Colorado, 80110, United States
Velocity Clinical Research, Durham

Durham, North Carolina, 27701, United States
Velocity Clinical Research, Gardena

Anderson, California, 90247, United States
Velocity Clinical Research, Grand Island

Grand Island, Nebraska, 68803, United States
Velocity Clinical Research, Grants Pass

Grants Pass, Oregon, 97527, United States
Velocity Clinical Research, Hampton

Hampton, Virginia, 23666, United States
Velocity Clinical Research, Huntington Park

Huntington Park, California, 90255, United States
Velocity Clinical Research, Kansas City

Kansas City, Kansas, 66210, United States
Velocity Clinical Research, Medford

Medford, Oregon, 97504, United States
Velocity Clinical Research, Mobile

Mobile, Alabama, 36608, United States
Velocity Clinical Research, Mt. Auburn

Cincinnati, Ohio, 45219, United States
Velocity Clinical Research, New Orleans

New Orleans, Louisiana, 70119, United States
Velocity Clinical Research, Norfolk

Norfolk, Nebraska, 68701, United States
Velocity Clinical Research, Phoenix

Phoenix, Arizona, 85006, United States
Velocity Clinical Research, Rockville

Rockville, Maryland, 20854, United States
Velocity Clinical Research, Salt Lake City

West Jordan, Utah, 84088, United States
Velocity Clinical Research, San Bernardino

San Bernardino, California, 92408, United States
Velocity Clinical Research, San Diego

La Mesa, California, 91942, United States
Velocity Clinical Research, Savannah

Savannah, Georgia, 31406, United States
Velocity Clinical Research, Spartanburg

Spartanburg, South Carolina, 29303, United States
Velocity Clinical Research, Suffolk, VA

Suffolk, Virginia, 23435, United States
Velocity Clinical Research, Union

Union, South Carolina, 29379, United States
Velocity Clinical Research, Van Nuys

Van Nuys, California, 91405, United States
Waco Cardiology Consultants

Waco, Texas, 76712, United States
Wichita Surgical Specialists

Wichita, Kansas, 67214, United States

Conditions

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OBESITY