Tiny study probes how heart rebounds after brief artery blockage
NCT ID NCT05023629
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how the heart's pumping function recovers after a short, controlled blockage of a coronary artery using a balloon. Six adults with stable coronary artery disease undergoing angioplasty had a balloon inflated in their artery for 90 seconds. Researchers measured heart wall motion before and after to see how quickly it returned to normal. The study was terminated early, so findings are very preliminary.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Intracoronary balloon inflation
- What this could lead to
- If successful, this could help doctors understand how the heart recovers after temporary blood flow blockage during angioplasty.
- What could go wrong
- This was a very small, early study with only 6 participants and was terminated early, so results are limited and may not apply to others.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
6 people
The number who actually took part.
- Started
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Sep 2021
- Finished
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Jan 2022
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age \>18 years. 2. Stable CAD with indication for PCI of a lesion in either of the following coronary segments: 1. 6 or 7 (proximal or mid left anterior descending coronary artery) 2. 11 (Proximal left circumflex coronary artery) 3. 1 or 2 (proximal right coronary artery) 3. Normal cardiac function in the myocardial segments subtended by the target vessel, as assessed by echocardiography at the time of coronary angiography. 4. Written informed consent obtained. Exclusion Criteria: 1. Pre-existing heart failure 2. Known pre-existing irreversible regional or global wall motion abnormalities affecting the myocardial segments subtended by the target vessel. 3. Severe valvulopathy 4. Thrombolysis In Myocardial Infarction (TIMI) flow \<3 in the target vessel.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Kardiologen
Gothenburg, 41345, Sweden
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Other studies related to the condition(s) this trial covers.
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