Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Heart failure device study aims to improve patient care

NCT ID NCT03366545

Knowledge-focused Sponsor: Biotronik SE & Co. KG Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows over 3,000 heart failure patients who have a BIOTRONIC CRT device implanted. Researchers will track hospitalizations, deaths, and device issues over time to understand how well the devices work in real life. The goal is to find ways to improve treatment and device settings for future patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Cardiac Resynchronization Therapy (CRT) device
What this could lead to
If successful, this could help doctors better predict heart failure events and improve CRT device settings for future patients.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly benefit participants. Results may not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

3,030 people

The number who actually took part.

Started

May 2018

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Representative population of CRTpatients at clinical sites

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Planned de novo implantation of or upgrade to a CRT system for treatment according to the intended use * Patient is able to understand the nature of the registry and has provided written informed consent * Patient is willing and able to use the CardioMessenger and accepts the Home Monitoring concept * Remote monitoring using the Home Monitoring® platform is planned for the patient Exclusion Criteria: * Standard contraindication for CRT * Already or previously implanted with CRT system * • Age \< 18 years * Participation in another interventional clinical investigation other than the registry-based trials of BIO\|STREAM.HF * Pregnant or breastfeeding

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Heart failure are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heart failure

Contacts and locations

Locations

  • Assuta Medical Center

    Ashdod, Israel

  • Ben-Gurion University of the Negev

    Beersheba, 84101, Israel

  • Bonifatius Hospital Lingen gGmbH

    Lingen, Germany

  • CH Saint Philibert

    Lomme, France

  • CH de Valence

    Valence, France

  • CHR de la Citadelle - Liège

    Liège, Belgium

  • CHU Montpellier

    Montpellier, France

  • CHU de Brest

    Brest, France

  • Canberra Heart Rhythm Foundation

    Canberra, Australia

  • Carl-von-Basedow-Klinikum Saalekreis GmbH

    Merseburg, Germany

  • Centre Hospitalier Bretagne Atlantique Prosper Chubert

    Vannes, France

  • Centre Hospitalier Lorient

    Lorient, France

  • Centre Hospitalier Louis Pasteur

    Chartres, France

  • Centre Hospitalier Mémorial de Saint-Lô

    Saint-Lô, France

  • Centre Hospitalier Universitaire de Saint-Étienne

    Saint-Etienne, France

  • Centre Hospitalier de Périgeux

    Périgueux, France

  • Centre Hospitalier de Rangueil

    Toulouse, France

  • Centro Médico Teknon

    Barcelona, 08022, Spain

  • Chaim Sheba Medical Center

    Tel Litwinsky, 52621, Israel

  • Changi General Hospital

    Singapore, Singapore

  • Chru de Tours

    Tours, France

  • Clinique Pasteur Toulouse

    Toulouse, France

  • Clinique du Millenaire

    Montpellier, France

  • Clinique les Fontaines

    Melun, France

  • East-Slovak Cardiology Institute (VUSCH)

    Košice, Slovakia

  • Fakultní nemocnice Olomouc

    Olomouc, 77900, Czechia

  • Far Eastern Memorial Hospital

    New Taipei City, Taiwan

  • Fujita Health University Hospital

    Toyoake, Japan

  • Gateway Private Hospital

    Umhlanga, South Africa

  • Gottsegen György Országos Kardiológiai Intézet

    Budapest, Hungary

  • HDZ Bad Oeynhausen

    Bad Oeynhausen, 32545, Germany

  • Hiroshima Prefectural Hospital

    Hiroshima, Japan

  • Hopital Pitie-Salpetriere

    Paris, France

  • Hopital de la Timone (CHU La Timone)

    Marseille, France

  • Hospital Espirito Santo de Evora

    Evora, Portugal

  • Hospital General Universitario de Alicante

    Alicante, Spain

  • Hospital General Universitario de Valencia

    Valencia, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Spain

  • Hospital Universitario Donostia

    Donostia / San Sebastian, Spain

  • Hospital Universitario La Fé

    Valencia, Spain

  • Hospital Universitario Virgen de la Victoria

    Málaga, Spain

  • Hospital Universitario de Bellvitge

    Barcelona, Spain

  • Hospital Universitario de Burgos

    Burgos, Spain

  • Hospital de Santa Cruz

    Carnaxide, Portugal

  • Hospital de Santa Maria

    Lisbon, Portugal

  • Hospital de Santo António

    Porto, Portugal

  • Hospital Álvaro Cunqueiro

    Vigo, Spain

  • Hôpital Haut Lévêque

    Pessac, France

  • Hôpital Privé / Institute Jaques Cartier

    Massy, France

  • Hôpital privé Clairval

    Marseille, 13009, France

  • Hôpital privé du Confluent

    Nantes, France

  • Hôpitaux Universitaires de Strasbourg

    Strasbourg, France

  • Imelda Ziekenhuis

    Bonheiden, 2820, Belgium

  • Institute for Clinical and Experimental Medicine (IKEM)

    Prague, Czechia

  • Johannes Wesling Klinikum Minden

    Minden, Germany

  • Juntendo University Hospital

    Tokyo, Japan

  • KMG Klinikum Güstrow

    Güstrow, Germany

  • Kaohsiung Veterans General Hospital

    Kaohsiung City, Taiwan

  • Kaplan Medical Center

    Rehovot, Israel

  • Kepler Universitätsklinikum

    Linz, Austria

  • Kettering General Hospital

    Kettering, United Kingdom

  • Kitasato University Hospital

    Sagamihara, Japan

  • Klinikum der LMU / Campus Großhadern

    München, 81377, Germany

  • Klinikum der Universität Jena

    Jena, 07743, Germany

  • Kokura Memorial Hospital

    Fukuoka, Japan

  • Krankenhaus Buchholz und Winsen AöR

    Buchholz, Germany

  • Le Centre Hospitalier Universitaire de CAEN

    Caen, France

  • Life Westville

    Westville, South Africa

  • Liverpool Hospital

    Liverpool, Australia

  • Lyell McEwin Hospital

    Elizabeth Vale, Australia

  • Maria Heimsuchung - Carita-Klinik Pankow

    Berlin, 13187, Germany

  • Medical University of Lodz

    Lodz, Poland

  • Mediclinic Midstream

    Pretoria, South Africa

  • Mediclinic Panorama Hospital

    Cape Town, South Africa

  • Mediclinic Pietermaritzburg

    Pietermaritzburg, South Africa

  • Medizinische Universität Wien

    Vienna, Austria

  • Meir Medical Center

    Kfar Saba, Israel

  • Nemocnice České Budějovice

    České Budějovice, Czechia

  • NÚSCH Bratislava a.s.

    Bratislava, Slovakia

  • Ospedale San Raffaele

    Milan, Italy

  • Pauls Stradins Clinical University Hospital

    Riga, Latvia

  • Policlinico Casilino

    Roma, Italy

  • Rabin Medical Center

    Petah Tikva, 49100, Israel

  • Russells Hall Hospital

    Dudley, United Kingdom

  • Saitama Medical University International Medical Center

    Saitama, Japan

  • Schüchtermann Klinik, Herzzentrum Osnabrück-Bad Rothenfelde

    Rothenfelde, Germany

  • Semmelweis Medical University

    Budapest, Hungary

  • Shaare Zedek Medical Center

    Jerusalem, Israel

  • Shamir Medical Center

    Ẕerifin, 70300, Israel

  • St. Peter's Hospital

    Chertsey, United Kingdom

  • State Hospital of Cardiology

    Balatonfüred, Hungary

  • Städtische Kliniken Neuss -Lukaskrankenhaus- GmbH

    Neuss, Germany

  • Städtisches Klinikum Brandenburg GmbH

    Brandenburg, Germany

  • Städtisches Klinikum St.Georg

    Leipzig, Saxony, 04129, Germany

  • Sydney Adventist Hospital

    Sydney, Australia

  • Szpital Kliniczny Przemienienia Pańskiego

    Poznan, Poland

  • SÚSCCH

    Banská Bystrica, Slovakia

  • The Canberra Hospital

    Canberra, Australia

  • The National Cardiology Institute of Stefan Cardinal Wyszynski - National Research Institute

    Warsaw, Poland

  • The University of Pécs

    Pécs, Hungary

  • Tokai University Hospital

    Kanagawa, Japan

  • UZ Brussel

    Brussels, 1090, Belgium

  • Unitas Hospital

    Pretoria, South Africa

  • Universitätsklinikum Erlangen

    Erlangen, Germany

  • Universitätsklinikum Giessen und Marburg

    Giessen, 35392, Germany

  • Universitätsklinikum Münster

    Münster, Germany

  • Universitätsklinikum Schleswig-Holstein (UKSH) - Campus Lübeck

    Lübeck, Germany

  • Universitätsklinikum St. Pölten

    Sankt Pölten, Austria

  • Universitätsklinikum Würzburg

    Würzburg, Germany

  • Universitätsspital Zürich

    Zurich, Switzerland

  • Westmead Hospital

    Westmead, 2145, Australia

  • Westmead Private Hosptial

    Westmead, Australia

  • Wolfson Medical Center

    Holon, Israel

  • Zentralklinik Bad Berka GmbH

    Bad Berka, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.