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Spinal injury heart risk under the microscope

NCT ID NCT07456722

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 28, 2026 · Updated 2 times

Summary

This study looks at whether people with long-term spinal cord injury who also have a condition called autonomic dysreflexia (sudden high blood pressure) have changes in their heart structure. Researchers will use MRI scans to compare two groups: 24 people with high-level injury and dysreflexia, and 24 people with low-level injury without dysreflexia. The goal is to understand if dysreflexia is a hidden risk factor for heart problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be recruited from all patients with a chronic spinal cord injury arriving for a routine urology check-up at the Swiss Paraplegic Center in Nottwil, Switzerland

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * adults aged 18 years or older * long-term (\>10 years), motor-complete SCI/D (AIS A and B) * Group A (24 individuals): high-level (\>Th6) SCI/D and autonomic dysreflexia * Group B (24 individuals): low-level (\<Th10) SCI/D without autonomic dysreflexia * signed informed consent Exclusion Criteria: * congenital heart defects * valvular disease(s) * cardiomyopathy * medium to severe arrhythmia * myocardial infarction * comorbidities causing morphologic heart changes including primary hypertension, aortic stenosis * comorbidities causing arterial hypertension * use of anti-hypertensive treatment * smokers * individuals after sacral deafferentation surgery * pregnancy * active implanted medical devices * claustrophobia * inability to comply with the measurement procedures

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Swiss Paraplegic Center

    RECRUITING

    Nottwil, 6207, Switzerland

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