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Heart attack prevention showdown: proactive care vs. standard care

NCT ID NCT03439267

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a proactive approach to preventing heart disease, with or without using a coronary calcium scan, works better than standard care. About 5,765 adults at moderate risk for heart problems but with no known heart disease are taking part. The goal is to see if this strategy reduces major events like heart attacks, strokes, or death.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

5,765 people

The number who actually took part.

Started

Mar 2018

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Male subjects 50 to 80 years of age or female subjects 60 to 80 years of age, of any ethnic origin 2. Ability to understand and provide agreement to study participation, which must be obtained prior to initiation of any study procedures 3. No known history, as documented in the EHR, of coronary artery disease, cerebrovascular disease, peripheral vascular disease, or diabetes mellitus at enrollment 4. Willing and able to provide access to their EHR until study end 5. Willing and able to undergo a computed tomography (CT) coronary artery calcium screening test 6. Current and/or past patients seen at Intermountain facilities and who have accessible EHR at the facility(ties) where they are seen. Exclusion Criteria: 1. Patients who have active on-going cancer or are on dialysis 2. Any evidence of statin use prior to study participation 3. Participation in any other clinical trials involving investigational or marketed products within 30 days prior to entry in the study 4. Any evidence of a CAC test within the last 5 years prior to screening 5. The Study Doctor(s) determine(s) that the subject is not eligible for participation in this research study 6. The subject is non-English speaking, and therefore may be unable to fully understand the written and spoken instructions that may relate to the proper conduct of the trial

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Intermountain Medical Center and Intermountain Clinics

    Murray, Utah, 84143, United States