Can we spot heart amyloidosis before it strikes?
NCT ID NCT05489549
First seen Jun 17, 2026 · Last updated Jun 17, 2026
Summary
This study aims to find early signs of a heart condition called transthyretin cardiac amyloidosis in Black adults who carry a specific genetic change (V122I TTR) but have no heart failure symptoms. Researchers will use advanced heart scans and blood tests to detect amyloid buildup and identify markers of disease progression. The goal is to improve early diagnosis so that treatments can start sooner, potentially preventing severe heart damage.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.