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Wisdom tooth healing boosted by blood gels and laser?

NCT ID NCT07324213

Knowledge-focused Sponsor: Medical Innovation Center Wroclaw Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether placing a gel made from a patient's own blood into the socket after wisdom tooth removal, along with low-level laser therapy, can improve healing. 122 adults had their impacted wisdom teeth removed and were assigned to different combinations of these treatments. Researchers measured pain, swelling, mouth opening, and bone regrowth over several months to see which approach worked best.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Autologous platelet concentrates (Advanced Platelet-Rich Fibrin and Concentrated Growth Factors) and low-level laser therapy
What this could lead to
If successful, this could point toward a standard approach to reduce pain and speed bone healing after wisdom tooth extraction.
What could go wrong
This is a completed study with known safe procedures, but the results may not apply to all patients or tooth types. The improvements may be small and not change current practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

122 people

The number who actually took part.

Started

Jan 2020

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 40 years. * Indication for surgical extraction of a partially or fully impacted mandibular third molar. * Generally healthy individuals without systemic diseases. * Ability to provide written informed consent. * Willingness to attend scheduled follow-up visits. Exclusion Criteria: * Presence of systemic diseases or metabolic disorders. * Pregnancy or breastfeeding. * Smoking. * Recent antibiotic therapy. * Poor oral hygiene. * Exceptionally difficult tooth position. * Surgical procedure exceeding the expected duration. * Inability to achieve primary wound closure. * Failure to comply with follow-up visits.

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar bone loss Impacted mandibular third molar Impacted mandibular third molar extraction

Contacts and locations

Locations

  • Medyczne Centrum Innowacji Wrocław Sp. z o.o.

    Wroclaw, Poland

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