Cell injection aims to repair damaged livers in early trial

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years at the time of informed consent; sex unrestricted. * Diagnosis of decompensated cirrhosis established according to the Chinese Guidelines for the Diagnosis and Treatment of Liver Cirrhosis (2019 Edition) and attributable to: hepatitis B, hepatitis C, alcohol, autoimmune disease, metabolic-associated fatty liver disease, or other less common aetiologies when deemed appropriate by the investigator. * Karnofsky Performance Status (KPS) ≥ 60 (see Appendix 6). * Presence of a vascular access route judged safe for selective catheterisation of the proper hepatic artery. * For subjects with hepatitis B or C cirrhosis: HBV-DNA ≤ 50 IU/mL and HCV-RNA below the limit of quantification at screening; for alcohol-related cirrhosis: documented abstinence for ≥ 6 months. * Ability to understand the study procedures and willingness to comply; written informed consent obtained from the subject or legally authorised representative. Exclusion Criteria: * Known hypersensitivity to HCL001 Cell Injection or any of its excipients. * Child-Pugh score ≥ 13 (see Appendix 1 for scoring and classification). * Cavernous transformation of the portal vein. * Serum total bilirubin \> 10 × the upper limit of normal (ULN). * Hepatocellular carcinoma or any other concurrent malignancy. * Inability to cooperate or unwillingness to comply with protocol requirements. * Bleeding diathesis (e.g., haemophilia) or platelet count \< 40 × 10⁹/L despite platelet-raising therapy. * Use of anticoagulant or antiplatelet agents within 7 days prior to dosing. * Grade ≥ 3 hepatic encephalopathy within 3 months before dosing (grading criteria in Appendix 2). * Previous transjugular intrahepatic portosystemic shunt (TIPS) or requirement/planned TIPS during the study. * History of venous thrombosis, including portal vein thrombosis (PVT) Grade ≥ 2 (grading criteria in Appendix 9), deemed unsuitable by the investigator. * Severe dysfunction of vital organs (heart, lung, brain, kidney): Pulmonary: severe emphysema, pulmonary embolism, or any pulmonary disorder significantly impairing pulmonary function. Cardiac history meeting any of the following: 1. Decompensated heart failure (NYHA Class III-IV); 2. Unstable angina within 6 months before dosing. Chronic kidney disease (CKD) Stage 4-5. * Inadequately controlled diabetes despite treatment: HbA1c ≥ 8 % or fasting plasma glucose ≥ 10 mmol/L. * Pregnancy or lactation women; or inability/unwillingness to use Investigator-approved contraceptive methods during the study and for 6 months after study completion. * Participation in another interventional clinical trial within 3 months before screening, or prior receipt of any stem-cell therapy. * Positive human immunodeficiency virus (HIV) antibody. * Active infection (defined as an infection, other than intra-abdominal, requiring intravenous antibiotics) within 2 weeks before screening, deemed unsuitable by the investigator. * Ascites with concurrent intra-abdominal infection \[defined as: 1. Positive ascitic fluid culture; or 2. Ascitic polymorphonuclear neutrophil (PMN) count ≥ 250 × 10⁶/L\], deemed by the Investigator as unsuitable for trial participation. * History of drug abuse or psychiatric disorders. * Any other condition or circumstance-including concomitant disease, therapy, procedure, surgery, or clinically significant laboratory abnormality-that, in the opinion of the investigator, could interfere with study conduct, impose additional risk to the subject, or preclude safe participation or completion of the study.