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Grip strength may reveal hidden clues about liver vein pressure

NCT ID NCT07289698

Knowledge-focused Sponsor: Shanxi Provincial People's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 64 adults with liver cirrhosis and a history of variceal bleeding who were scheduled for a TIPS procedure. Researchers measured handgrip strength and then checked how it changed blood pressure in the portal and left gastric veins. The goal was to see if muscle function is linked to vein pressure, which could help understand complications of cirrhosis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

64 people

The number who actually took part.

Started

Dec 2025

Finished

Apr 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This observational study was performed in two centers in China (The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology \[Luoyang\], and Shanxi Provincial People's Hospital \[Taiyuan\]) . They serve as the major tertiary referral center for the management of liver cirrhosis and its complications in our country.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * adult patients (≥18 years of age) with cirrhosis and a history of variceal bleeding, who were preparing for TIPS creation for secondary prophylaxis against variceal bleeding Exclusion Criteria: * Severe congestive heart failure, or severe untreated valvular heart disease * Moderate to severe pulmonary hypertension * Uncontrolled systemic infection * Lesions (e.g., cysts) or tumors in the liver parenchyma that preclude TIPS creation * Overt hepatic encephalopathy * Unrelieved biliary obstruction * Child-Pugh score \> 13 * Model for end-stage liver disease (MELD) score \> 18 * International normalized ratio (INR) \> 5 * Platelet count \< 20×109/mm3 * Participants who had undergone hand or wrist surgery within the previous 3 months or were unable to hold the dynamometer with the testing hand were excluded from the study.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Handgrip strength Transjugular intrahepatic portosystemic shunts (TIPS)

Contacts and locations

Locations

  • Shanxi Provincial People's Hospital

    Taiyuan, Shanxi, 030012, China

  • The First Affiliated Hospital of Henan University of Science and Technology

    Luoyang, Henan, 471003, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.