New hand therapy may ease pain for arthritis patients with sensitive nerves
NCT ID NCT07598240
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding desensitization exercises to the usual hand rehab program can help rheumatoid arthritis patients who have central sensitization—a condition where the nervous system is extra sensitive to pain. About 81 adults with mild-to-moderate RA will be split into two groups based on their central sensitization status. The goal is to see if the extra exercises improve pain, hand strength, and daily function better than standard rehab alone.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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81 people
The number who actually took part.
- Started
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Aug 2025
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion \*Rheumatoid Arthritis Group Without Central Sensitization (Group 1): * Being between 18-75 years of age * Not having had upper extremity surgery within the last 1 year * Patients without active arthritis * No change in medical treatment in the last 3 months * Having mild-moderate disease activity according to DAS28 \*Rheumatoid Arthritis Group with Central Sensitization (Group 2): * Being between 18-75 years of age * Not having had upper extremity surgery within the last 1 year * Patients without active arthritis * No change in medical treatment in the last 3 months * Having mild-moderate disease activity according to DAS28 \*Rheumatoid Arthritis Group with Central Sensitization (Group 3): * Being between 18-75 years of age * Not having had upper extremity surgery within the last 1 year * Patients without active arthritis * No change in medical treatment in the last 3 months * Having mild-moderate disease activity according to DAS28 Criteria: \- Exclusion Criteria: * Having had surgery on the extremity to be treated within the last 6 months * Patients with active arthritis * Patients with cognitive deficit * Patients who do not consent to participate in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Haydarpaşa Numune Eğitim Ve Araştirma Hastanesi Validebağ Ek Hizmet Binasi
Istanbul, ÜSKÜDAR, 34674, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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