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Could a daily 5-Minute mask soothe nerve pain?

NCT ID NCT07583797

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a special hand and foot mask designed to ease nerve pain caused by chemotherapy or diabetes. Sixty adults will apply the mask daily for 5 minutes over one week. Researchers will measure changes in symptoms and quality of life using questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hand and foot mask containing TRPM8 activators
What this could lead to
If it works, this could offer a simple, non-drug way to reduce nerve pain and improve quality of life for people with chemotherapy- or diabetes-related nerve damage.
What could go wrong
This is a small, early-phase pilot study with only 60 people and a short 7-day treatment period. Results may not apply to everyone, and the effect might be small or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

60 people

The number who actually took part.

Started

Nov 2025

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients aged 20 years or older who are currently receiving or have previously received chemotherapy and have clinical features of chemotherapy-induced peripheral neuropathy (CIPN). 2. Diabetic patients aged 20 years or older who have clinical features of diabetic peripheral neuropathy (DPN). 3. Patients who meet criteria 1 or 2, are willing to participate, and are able to sign an informed consent form. Exclusion Criteria: 1. Poorly controlled diabetes (HbA1c \> 8%). 2. Peripheral vascular disease. 3. Chronic kidney disease (eGFR \< 30 ml/min/m²). 4. Depression, history of surgery on the hands, feet, or back. 5. Skin conditions such as leprosy and connective tissue disorders, familial neuropathy. 6. Pregnant or breastfeeding women. 7. Individuals with allergic symptoms. 8. Individuals with a history of convulsions. 9. Individuals with G6PD deficiency (favism).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chung Shan Medical University Hospital

    Taichung, Taichung, 402306, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.