Could a daily 5-Minute mask soothe nerve pain?
NCT ID NCT07583797
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests a special hand and foot mask designed to ease nerve pain caused by chemotherapy or diabetes. Sixty adults will apply the mask daily for 5 minutes over one week. Researchers will measure changes in symptoms and quality of life using questionnaires.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- hand and foot mask containing TRPM8 activators
- What this could lead to
- If it works, this could offer a simple, non-drug way to reduce nerve pain and improve quality of life for people with chemotherapy- or diabetes-related nerve damage.
- What could go wrong
- This is a small, early-phase pilot study with only 60 people and a short 7-day treatment period. Results may not apply to everyone, and the effect might be small or temporary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
60 people
The number who actually took part.
- Started
-
Nov 2025
- Expected to finish
-
Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
20 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients aged 20 years or older who are currently receiving or have previously received chemotherapy and have clinical features of chemotherapy-induced peripheral neuropathy (CIPN). 2. Diabetic patients aged 20 years or older who have clinical features of diabetic peripheral neuropathy (DPN). 3. Patients who meet criteria 1 or 2, are willing to participate, and are able to sign an informed consent form. Exclusion Criteria: 1. Poorly controlled diabetes (HbA1c \> 8%). 2. Peripheral vascular disease. 3. Chronic kidney disease (eGFR \< 30 ml/min/m²). 4. Depression, history of surgery on the hands, feet, or back. 5. Skin conditions such as leprosy and connective tissue disorders, familial neuropathy. 6. Pregnant or breastfeeding women. 7. Individuals with allergic symptoms. 8. Individuals with a history of convulsions. 9. Individuals with G6PD deficiency (favism).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chung Shan Medical University Hospital
Taichung, Taichung, 402306, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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