New hope for haemophilia a patients: immune training may restore clotting treatment
NCT ID NCT02207894
First seen Apr 25, 2026 · Last updated Apr 30, 2026 · Updated 1 time
Summary
This study tests a treatment called immune tolerance induction (ITI) in 300 people with haemophilia A who have developed inhibitors—antibodies that block standard clotting factor therapy. The goal is to retrain the immune system to accept the clotting factor again, using high doses of personalized factor products. Success is measured by lowering inhibitor levels and restoring normal factor activity and half-life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Haemophilia Centre Rhine Main
RECRUITINGFrankfurt am Main, Hesse, 60596, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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