Can intensive therapy boost motor skills in kids with SMA?
NCT ID NCT07223320
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 42 times
Summary
This pilot study tests whether combining intensive hand-arm and leg therapy with strength training can improve motor function in children with spinal muscular atrophy (SMA). Five children will attend one 6-hour session each weekend for 15 weeks. Researchers will check if the therapy is feasible and measure changes in motor skills.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Center for Cerebral Palsy Research, Teachers College, Columbia University
New York, New York, 10027, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) plus functional strength training (FST)
What this could lead to
If this therapy works, it could offer a new way to improve motor skills and strength in children with SMA, complementing existing disease-modifying treatments.
What could go wrong
This is a very small pilot study with only 5 participants and no control group, so results may not apply to all children with SMA. The therapy is also time-intensive (90 hours over 15 weeks), which may be hard for families to maintain.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.