Can intensive therapy boost motor skills in kids with SMA?
NCT ID NCT07223320
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether combining intensive hand-arm and leg therapy with strength training can improve motor function in children with spinal muscular atrophy (SMA). Five children will attend one 6-hour session each weekend for 15 weeks. Researchers will check if the therapy is feasible and measure changes in motor skills.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) plus functional strength training (FST)
- What this could lead to
- If this therapy works, it could offer a new way to improve motor skills and strength in children with SMA, complementing existing disease-modifying treatments.
- What could go wrong
- This is a very small pilot study with only 5 participants and no control group, so results may not apply to all children with SMA. The therapy is also time-intensive (90 hours over 15 weeks), which may be hard for families to maintain.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Center for Cerebral Palsy Research, Teachers College, Columbia University
New York, New York, 10027, United States
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Other studies related to the condition(s) this trial covers.