Can a common supplement boost muscle health? cleveland clinic investigates
NCT ID NCT05025865
First seen Nov 17, 2025 · Last updated Jun 19, 2026 · Updated 31 times
Summary
This early-stage trial at the Cleveland Clinic is studying how a specific type of hyaluronic acid (HA35) affects muscle protein in 24 healthy adults. Participants take either HA35 or a placebo capsule for three days, then undergo tests including muscle biopsies and a gut permeability test. The goal is to understand the basic mechanisms, not to treat any disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sodium hyaluronate (HA35)
What this could lead to
If successful, this could help scientists understand how HA35 affects muscle health, possibly pointing toward future treatments for muscle loss.
What could go wrong
This is a very early, small study in healthy people, not patients. It only tests short-term effects and may not lead to any treatment.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.