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Could a simpler pill combo beat the standard four-drug cocktail for stomach bug?

NCT ID NCT07179159

First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 34 times

Summary

This study tests whether a 14-day treatment using just two medications (vonoprazan and an antibiotic) works as well as the standard four-drug regimen for clearing H. pylori, a bacteria that can cause stomach ulcers and cancer. About 372 adults who have never been treated for H. pylori will take part. The main goal is to see how many people are cured of the infection, and researchers will also track side effects and how well participants stick to the treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Qilu Hospital of Shandong University

    RECRUITING

    Jinan, Shandong, 250012, China

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Qilu Hospital of Shandong University

    NOT_YET_RECRUITING

    Jinan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.