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Shorter antibiotic course may work just as well for stomach bug

NCT ID NCT07333001

First seen Jan 12, 2026 · Last updated Jun 22, 2026 · Updated 20 times

Summary

This study looked at 508 adults with H. pylori infection to see if a 7-day triple therapy (using vonoprazan, amoxicillin, and tetracycline) works as well as the standard 14-day dual therapy (vonoprazan and amoxicillin). Researchers compared how often the infection was cleared and any side effects. The goal is to find a shorter, effective treatment option.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Qilu Hospital of Shandong University

    Jinan, Shandong, 250012, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vonoprazan, amoxicillin, tetracycline

What this could lead to

If successful, a shorter 7-day treatment could be as effective as the standard 14-day regimen, making it more convenient for patients.

What could go wrong

This is a retrospective study, not a randomized trial, so results may be less reliable. The shorter regimen may not work as well in people with antibiotic resistance.

Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.