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Can your own blood help your jawbone heal better after a tooth extraction?

NCT ID NCT07011303

Disease control Sponsor: Tokat Gaziosmanpasa University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a substance made from a patient's own blood, called Horizontal Platelet Rich Fibrin (H-PRF), can help the jawbone heal better after a tooth is pulled. The goal is to create stronger bone for a future dental implant. Thirty adults aged 18-40 who need a tooth extraction and plan to get an implant will take part. Researchers will measure pain, swelling, and mouth opening to see if H-PRF makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Horizontal Platelet Rich Fibrin (H-PRF) – a concentrate from the patient's own blood
What this could lead to
If it works, this could improve bone healing after tooth extraction, making future dental implants more successful.
What could go wrong
This is a small, early study with only 30 participants. Results may not apply to everyone, and the benefit over standard care is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Volunteer ASA I individuals between the ages of 18-40 * Individuals with indication for tooth extraction * Patients who want to have implants after tooth extraction Exclusion Criteria: * Those who are pregnant or lactating * Those receiving anticoagulant or antiplatelet drug therapy * Those who received radiotherapy to the head and face area

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss periodontal disorder Tooth Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar bone loss Dental implant failed Tooth loss

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Tokat Gaziosmanpasa University, Faculty of Dentistry

    Tokat Province, 60100, Turkey (Türkiye)

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