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New weight loss drug GZR18 enters final testing phase

NCT ID NCT06728124

First seen Jan 04, 2026 · Last updated Jun 22, 2026 · Updated 25 times

Summary

This Phase 3 study tests an investigational drug called GZR18 for weight loss in 630 adults who are obese or overweight with related health issues. Participants receive either GZR18 or a placebo injection, and researchers measure weight change over time. The trial is double-blind and placebo-controlled to ensure reliable results.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beijing

    Beijing, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GZR18 injection

What this could lead to

If successful, this could provide a new medication option for significant weight loss in people with obesity or overweight.

What could go wrong

This is a Phase 3 trial, but results are not yet available. The drug may cause side effects or not prove more effective than placebo.

Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.