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Gut bacteria may hold key to predicting rectal cancer treatment success

NCT ID NCT07346729

First seen Jan 19, 2026 · Last updated May 23, 2026 · Updated 19 times

Summary

This study looked at 60 adults with locally advanced rectal cancer to see if bacteria in their gut and mouth could predict how well they respond to chemotherapy and radiation before surgery. Researchers collected stool and saliva samples before treatment and used machine learning to build a model that forecasts tumor shrinkage. The goal is to better personalize treatment, but this was an observational study, not a direct treatment trial.

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Contacts and locations

Locations

  • Nanfang Hosptial

    Guangzhou, Guangdong, 510515, China

Conditions

Explore the condition pages connected to this study.