Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Could a potato starch supplement ease gulf war illness?

NCT ID NCT05820893

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a dietary fiber supplement called resistant potato starch can improve gut health and quality of life in veterans with Gulf War Illness (GWI). About 52 veterans aged 50-85 with GWI and gut symptoms will take the supplement daily. Researchers will measure changes in gut bacteria and related metabolites, as well as symptom improvements.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Resistant potato starch (MSPrebiotic)
What this could lead to
If it works, this could point toward a simple dietary supplement to ease gut symptoms and improve quality of life for veterans with Gulf War Illness.
What could go wrong
This is a small Phase 2 trial with only 52 participants, so results may not apply to everyone. The supplement may not significantly change symptoms or microbiome composition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 52 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2025

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Ability to provide informed written consent 2. Willing to comply with all study procedures and be available for the duration of the study (including providing stool samples) 3. Meeting the modified Kansas GWI case definition\* with gut symptoms endorsed 4. Deployed to Persian Gulf during Operations Desert Storm or Desert Shield56.Aged 50-85 years old * Moderate to severe GWI symptoms lasting at least 6 months in a minimum of three of the six symptom domains (one of which must be fatigue). The symptom domains are: * Pain (joint pain, muscle pain) * Gastrointestinal (diarrhea, nausea, vomiting, cramping) * Respiratory (persistent cough, wheezing) * Skin (rashes) * Fatigue (sleep problems, fatigue) * Neurologic (memory problems, headaches, dizziness, mood changes) Exclusion Criteria: 1. A Known SARS-CoV-2 infection in the last 60 days and/or with a diagnosis of post-acute sequelae of COVID-19 (PASC, sometimes called long COVID) defined as COVID-19 symptoms lasting for greater than 6 months. 2. Subjects identified as, or appearing to, lack consent capacity 3. Alcohol abuse (greater than 14 drinks per week for men and 7 drinks per week for women) 4. Use of investigational drugs, biologics, or devices within 30 days prior to randomization. 5. Individuals who are pregnant, lactating or planning on becoming pregnant during the study. 6. Diagnosed inflammatory bowel disease, Crohn's disease, or Celiac's disease 7. Uncontrolled/untreated hypothyroidism 8. Previous gastrointestinal surgery (colorectal surgery, gastric bypass, intestinal resection) 9. Systemic antibiotics in the last 30 days 10. Fecal microbiota transplant in the last 30 days 11. Active dysphagia 12. Allergies to any of the ingredients in MSPrebiotic 13. Use of immunomodulatory medications in the last 30 days 14. Any other factor, condition, or medication not listed above the Investigators believe will affect the response in the gut or the interpretation of results.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Gulf war illness are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • William S. Middleton Memorial Veterans Hospital, Madison, WI

    RECRUITING

    Madison, Wisconsin, 53705-2254, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.