Gut bugs make good fats when fed right
NCT ID NCT06313606
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether eating certain dietary fats can boost the production of beneficial fats (called cyclopropane fatty acids) by gut bacteria. Ten healthy adults ate specific foods, and researchers measured these fats in their blood, urine, and stool. The goal was to see if this approach could one day help manage blood sugar, cholesterol, or fatty liver disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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10 people
The number who actually took part.
- Started
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May 2024
- Finished
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Aug 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men and women aged 18 to 50, with a Body Mass Index (BMI) categorized "normal" through "overweight" (18.5-29.9 kg/m2) and able to provide informed consent in English will be recruited to the study. Exclusion Criteria: * \- pregnancy or lactation * allergy or aversion to any of the foods that will be studied and/or provided * history of gastrointestinal disorders including ulcerative colitis, Crohn's disease, celiac sprue, hereditary non-polyposis colorectal cancer (HNPCC), familial adenomatous polyposis, pancreatic disease, or liver disease * history of any metabolic diseases (including, but not limited to: diabetes mellitus, hyperlipidemia) * previous gastrointestinal resection or bariatric surgery * bleeding disorders that preclude blood draws * history of kidney disease * recent hospital admissions (past 6 months) for heart disease (MI/CVA or CHF) or other CVD/CAD conditions under physician guided therapy * cancer under radiation or chemotherapy treatment that is active or within 6 months of treatment * regular alcohol intake of \> 2 drinks/day (equivalent to 720 mL of beer, 240 mL of wine, or 90 mL of spirits) and unwilling to abstain during the run-in week and test day * use of tobacco and/or marijuana, hookahs, e-cigarettes (e-cigs, vapes, etc.) and not willing to abstain during the run-in week and test day * use of illicit drugs and not willing to abstain during the run-in week and test day * BMI greater than 30 kg/m2 or below 18.5 kg/m2 * regular (daily to weekly) use of over the counter (OTC) weight-loss aids, anti-acids or anti-inflammatories, and unwilling or unable to stop taking during the run-in week and test day * regular OTC dietary supplements that interfere with the test foods being studied including pills, chewables, liquids or powders for the following: fiber, fish oil (including cod liver oil), probiotics, and unwilling or unable to stop taking during the run-in week and test day * oral or IV antibiotic use in the past 6 months (could defer participation until 6 months post-completion of course of antibiotics) * seated blood pressure \>140/90 mmHg * fasting clinical lab tests outside acceptable values as ascertained at the screening blood draw * current use of specific prescription medication(s) that could impact gut physiology, gut microbiota, or other systems relevant to metabolism and fat PK * inability to freely give informed consent in English
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of California, Davis School of Medicine
Sacramento, California, 95817, United States