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Gummy smile study seeks answers in 100 young adults

NCT ID NCT07548398

Knowledge-focused Sponsor: University of Roma La Sapienza Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find out how often gummy smiles and a related condition called altered passive eruption occur in healthy young adults aged 18 to 50. Researchers will measure gum display during smiling and tooth lengths using photos and dental tools. The results will help understand these common aesthetic concerns better.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The population will include individuals with and without excessive gingival display, in order to assess the prevalence of gummy smile and its association with altered passive eruption and related anatomical and aesthetic parameters. Particular attention will be given to the second sextant, which represents the area most frequently involved in gingival display. All participants will undergo a non-invasive clinical and photographic assessment aimed at evaluating gingival exposure, clinical crown dimensions, and other relevant anatomical features. In addition, patient-reported outcomes regarding aesthetic perception and psychosocial impact will be collected.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female subjects; * Age between 18 and 50 years; * Periodontally healthy subjects; * Patients with no history of orthodontic treatment; * Patients without gingival hypertrophy or hyperplasia. Exclusion Criteria: * Age \< 18 or \> 50 years; * Patients diagnosed with Stage I-IV periodontitis; * Patients currently undergoing orthodontic treatment; * Patients with severe dental crowding in the second sextant; * Patients taking medications associated with gingival hypertrophy or -hyperplasia; * Patients unwilling to provide informed consent; * Patients with fixed or removable prostheses in the second sextant; * Patients with a history of surgical procedures in the second sextant; * Patients with uncontrolled diabetes or neuropsychiatric disorders; * Patients with infectious diseases; * Pregnant or breastfeeding women, or those with suspected pregnancy; * Patients taking bisphosphonates; * Oncologic patients and those undergoing head and neck radiotherapy or receiving chemotherapy; * Patients with alcohol or drug abuse.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Altered passive eruption of teeth

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sapienza università di Roma

    RECRUITING

    Roma, RM, 00161, Italy

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