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Deep dental cleaning may protect kidneys in diabetics, new study suggests

NCT ID NCT07256613

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 25, 2026 · Updated 2 times

Summary

This study looks at whether deep cleaning for gum disease can improve kidney health in people with uncontrolled type 2 diabetes. 46 adults with both conditions will either get gum treatment right away or after a delay. Researchers will measure kidney markers like creatinine and urea in blood tests at the start and after 90 days to see if gum care makes a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

46 people

The number who actually took part.

Started

May 2025

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults between 30 and 65 years of age * Men and women previously diagnosed with type 2 diabetes mellitus for at least one year * Participants with uncontrolled diabetes, defined as HbA1c ≥ 7% * Presence of moderate to severe gum disease, Stage II or Stage III periodontitis, as determined by dental examination * Estimated glomerular filtration rate (eGFR) of 60 mL/min/1.73 m² or higher * Willing and able to provide written informed consent Exclusion Criteria: * Critically ill individuals or those unable to communicate effectively * Pregnant or breastfeeding women * Women currently using hormone replacement therapy or oral contraceptives within the past six months * Individuals taking steroidal drugs, nonsteroidal anti-inflammatory drugs (NSAIDs), or other anti-inflammatory medications within the past three months, except low-dose aspirin up to 75 mg daily * Participants with a recent history of major blood loss, trauma, or gastrointestinal bleeding * Use of antibiotics within the last month * History of fever or vomiting lasting more than one week within the last month * Regular tobacco or alcohol users * Individuals with any other chronic disease or condition that could interfere with study outcomes * Individuals unwilling or unable to comply with study procedures or follow-up visits

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dow University of Health Scinces

    Karachi, Sindh, 75330, Pakistan