Can a blood clot or gum graft erase black triangles between teeth?
NCT ID NCT07746622
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This trial tests two ways to rebuild the small triangle of gum tissue between teeth, which can shrink and leave dark gaps. One method uses a graft of the patient's own gum tissue, while the other uses a special blood-derived clot. The study will enroll 34 adults with gum recession in the front teeth and measure how well each technique fills the gap over six months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- De-epithelialized gingival graft (DGG) or Titanium-Prepared Platelet-Rich Fibrin (T-PRF) used in a tunnel technique procedure
- What this could lead to
- If successful, this could identify a better method for rebuilding lost gum tissue, potentially improving smile aesthetics and oral health.
- What could go wrong
- This is a small, early-stage trial, and results may not apply to everyone. Surgery carries risks like infection, bleeding, or graft failure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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34 people
The number who actually took part.
- Started
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Nov 2022
- Finished
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Mar 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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25 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 25 and 70 years. * Presence of papilla loss in the anterior region of the maxilla or mandible. * Classification of papilla loss as Class 1 or 2 * Absence of systemic diseases. * No bleeding disorders that could interfere with the surgery. * Non-smoker and non-alcohol consumer. * Not pregnant or breastfeeding. * Absence of fillings, prostheses, or root canal treatments in the relevant teeth. * No prior surgical interventions in the target area. Exclusion Criteria: * Smoking or alcohol consumption. * Presence of systemic diseases * Patients who did not attend postoperative follow-up appointments regularly. * Pregnant or breastfeeding individuals.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Dentistry, Pamukkale University
Denizli, Pamukkale, 20160, Turkey (Türkiye)
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Pamukkale University Faculty of Dentistry
Denizli, Denizli, 20160, Turkey (Türkiye)
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