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Can a blood clot or gum graft erase black triangles between teeth?

NCT ID NCT07746622

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests two ways to rebuild the small triangle of gum tissue between teeth, which can shrink and leave dark gaps. One method uses a graft of the patient's own gum tissue, while the other uses a special blood-derived clot. The study will enroll 34 adults with gum recession in the front teeth and measure how well each technique fills the gap over six months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
De-epithelialized gingival graft (DGG) or Titanium-Prepared Platelet-Rich Fibrin (T-PRF) used in a tunnel technique procedure
What this could lead to
If successful, this could identify a better method for rebuilding lost gum tissue, potentially improving smile aesthetics and oral health.
What could go wrong
This is a small, early-stage trial, and results may not apply to everyone. Surgery carries risks like infection, bleeding, or graft failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

34 people

The number who actually took part.

Started

Nov 2022

Finished

Mar 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 25 and 70 years. * Presence of papilla loss in the anterior region of the maxilla or mandible. * Classification of papilla loss as Class 1 or 2 * Absence of systemic diseases. * No bleeding disorders that could interfere with the surgery. * Non-smoker and non-alcohol consumer. * Not pregnant or breastfeeding. * Absence of fillings, prostheses, or root canal treatments in the relevant teeth. * No prior surgical interventions in the target area. Exclusion Criteria: * Smoking or alcohol consumption. * Presence of systemic diseases * Patients who did not attend postoperative follow-up appointments regularly. * Pregnant or breastfeeding individuals.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dentistry, Pamukkale University

    Denizli, Pamukkale, 20160, Turkey (Türkiye)

  • Pamukkale University Faculty of Dentistry

    Denizli, Denizli, 20160, Turkey (Türkiye)

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