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Could a blood concentrate improve gum healing around dental implants?

NCT ID NCT07346391

Disease control Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times

Summary

This study tests whether adding a patient's own platelet-rich fibrin (PRF) to a gum graft improves healing and appearance around dental implants. Twenty-two people with thin gum tissue will receive either the combined graft or the standard graft alone. Researchers will measure gum width, pain, and aesthetics over six months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Platelet-Rich Fibrin (PRF) combined with a strip free gingival graft
What this could lead to
If it works, this could offer a better way to increase gum tissue around dental implants, reducing pain and improving appearance.
What could go wrong
This is a very small, early-stage trial with only 22 people. The benefits may not be significant compared to the standard method, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

22 people

The number who actually took part.

Started

Dec 2025

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients meeting the following criteria are eligible for the study: * Prosthetic Phase: Patients scheduled for the prosthetic phase of dental implant treatment. * Keratinized Mucosa: Keratinized mucosa height (buccal or lingual) of less than 2 mm around the implant. * Systemic Health: Systemic health status classified as ASA I or II according to the American Society of Anesthesiologists classification. * Oral Hygiene: Good oral hygiene, defined by a mean full-mouth plaque index (PlI) of ≤ 1. Exclusion Criteria: * Patients meeting any of the following criteria will be excluded from the study: * Systemic Conditions: Presence of systemic diseases or use of medications known to affect the oral mucosa or gingival health. * Periodontal Health: Untreated periodontal disease and/or peri-implant diseases. * Surgical History: History of mucogingival surgery at the intended surgical site. * Pregnancy/Lactation: Pregnant or breastfeeding women. * Oral Hygiene: Poor oral hygiene, defined by a mean full-mouth plaque index (PlI) \> 1. * Smoking: Current smokers.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental implants

Contacts and locations

Locations

  • Phòng Khám Chuyên Khoa Răng Hàm Mặt Đại Học Y Dược Thành Phố Hồ Chí Minh

    HỒ CHÍ MINH, VIỆT NAM, 123456789, Vietnam

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