Gum graft secrets revealed: 3D study tracks tissue changes
NCT ID NCT07617987
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how free gum grafts shrink and change after being moved to a new spot in the mouth. Twenty adults with thin gums will each get two grafts from the same area of the palate, taken 63 days apart. Researchers will use 3D scans and tissue analysis to understand the healing process and what affects graft size.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Systemically healthy, non-smoking individuals aged 18-65 years with insufficient keratinized gingiva (\<2 mm; Lang \& Löe, 1972) involving the bilateral mandibular canine and/or premolar regions will be included in the study.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Individuals aged between 18 and 65 years, * Absence of any systemic disease that may adversely affect periodontal health and wound healing, * Non-smokers, * Periodontally healthy individuals, * Mean plaque index (PI) score \<1 following non-surgical periodontal therapy (NSPT), * No use of antibiotics or anti-inflammatory drugs within the last 3 months, * Not being pregnant or breastfeeding, * Willingness to participate in the study by signing the informed consent form. Exclusion Criteria: * Presence of any systemic disease contraindicating surgical procedures, * Use of medications or supplements affecting bleeding or wound healing, * Presence of uncontrolled diabetes mellitus (HbA1c \>7), * Pregnancy or breastfeeding, * History of chemotherapy or radiotherapy within the last 6 months, * History of antibiotic use within the last 3 months, * Palatal mucosal thickness \<3 mm or presence of palatal torus, * Presence of deep and narrow (U-shaped) or shallow palatal vaults interfering with palatal measurements, * Non-compliance with treatment or follow-up protocols.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Biruni University
Istanbul, Turkey (Türkiye)
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