Gum graft may boost implant infection treatment

NCT ID NCT06305000

Disease control Sponsor: Biruni University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a gum graft to standard deep cleaning helps treat peri-implant mucositis, a common inflammation around dental implants. Researchers will compare four groups of 16 people each: healthy implants, inflamed implants with enough gum tissue, inflamed implants with thin gum tissue getting only cleaning, and inflamed implants with thin gum tissue getting both cleaning and a graft. They will measure gum health and inflammatory markers over 7 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: free gingival graft (gum tissue graft)
What this could lead to: If it works, this could show that adding a gum graft improves treatment for inflammation around dental implants, potentially reducing the need for more invasive procedures.
What could go wrong: This is a small, early-stage study with only 48 people. The graft is a surgical procedure with risks like pain, bleeding, or graft failure. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2024

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individual dental implants with a fixed prosthetic restoration that has been functional for at least 1 year * No systemic disease and medication use that may affect periodontal or peri-implanter tissues * Not receiving periodontal treatment in the last 6 months * Volunteering to participate in the study Exclusion Criteria: * Prosthetic restorations with an excessive contour which do not allow peri-implant pocket measurement * Being pregnant or breastfeeding, * Autoimmune and/or inflammatory diseases of the oral cavity, * Active periodontal disease * Smokers (≥ 10 cigarettes per day) * Improperly positioned implants

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Peri implant mucositis

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

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Gum graft may boost implant infection treatment

What the study statuses mean