New study compares high-tech gum cleaning to traditional methods
NCT ID NCT07243145
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study looked at two ways to clean below the gumline in 80 adults with early-stage gum disease. One group received Guided Biofilm Therapy, a newer technique, while the other got conventional cleaning with hand tools and an ultrasonic device. Researchers measured gum health and immune markers in the fluid around teeth before treatment and at one and three months after.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Guided Biofilm Therapy (GBT) versus conventional scaling and root planing
- What this could lead to
- If successful, this could help dentists choose the most effective cleaning technique to reduce gum inflammation and improve long-term oral health.
- What could go wrong
- This is a small, completed study with only 80 participants, so results may not apply to everyone. It measured short-term changes, not long-term tooth loss or disease progression.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
80 people
The number who actually took part.
- Started
-
Oct 2024
- Finished
-
May 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who applied to Niğde Ömer Halisdemir University Faculty of Dentistry Periodontics Clinic between 15.10.2024 and 15.12.2024 for periodontal treatment, volunteered to participate in the study and met the following criteria were included in the study. Written consent was obtained from volunteer patients for the research. The patients were evaluated by a single periodontologist (SND), and patients with mild to moderate periodontitis (Stage 1-2) who required supragingival and subgingival calculus removal were included in the study.
- Ages
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18 to 40 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Systemically healthy (no known chronic diseases) * Completed periodontal diagnostic data (Gingival Index, Plaque Index, Periodontal pocket depths, Attachment loss, Radiological data, and Bone loss data) * Did not take anti-inflammatory drugs in the previous month * Volunteered to participate with Stage 1-2 periodontitis. Exclusion Criteria: * Patients with systemic diseases * Pregnant or lactating patients * Smokers * Patients who did not wish to participate in the study were excluded
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Nigde Omer Halisdemir University
Niğde, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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