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New cancer drug candidate GS-9716 enters first human tests

NCT ID NCT05006794

First seen Jan 09, 2026 · Last updated May 23, 2026 · Updated 26 times

Summary

This early-phase study tests a new drug called GS-9716 (zamzetoclax) in about 145 people with advanced solid tumors that have not responded to other treatments. The drug is given alone or with other cancer therapies to find the safest dose and check for side effects. The goal is to see if it can help control the disease, not to cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hadassah Medical Center- Ein Kerem

    Jerusalem, 91120, Israel

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Montefiore Medial Center - Montefiore Medical Park

    The Bronx, New York, 10467, United States

  • Novant Health Cancer Institute - Elizabeth (Breast Cancer)

    Charlotte, North Carolina, 28204, United States

  • Oregon Health Oregon Health & Sciences University-Knight Cancer Institute

    Portland, Oregon, 97239, United States

  • Rambam Health Care Campus

    Haifa, 31096, Israel

  • START Midwest

    Grand Rapids, Michigan, 49546, United States

  • START Mountain Region

    West Valley City, Utah, 84119, United States

  • START San Antonio

    San Antonio, Texas, 78229, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73104, United States

  • Tel-Aviv Sourasky Medical Center

    Tel Aviv, 6423906, Israel

  • University of Colorado Hospital - Anschutz Cancer Pavilion (ACP)

    Aurora, Colorado, 80045, United States

Conditions

Explore the condition pages connected to this study.