New protocol aims to start lifesaving care for kids with sepsis en route to hospital
NCT ID NCT01293500
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 36 times
Summary
This study tested whether a standardized, goal-directed treatment plan given during ambulance transport could improve outcomes for children with Systemic Inflammatory Response Syndrome (SIRS), a severe inflammatory condition. Researchers planned to compare outcomes before and after implementing the protocol in 230 children. The trial was terminated early, so its findings are limited.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Arkansas Children's Hospital
Little Rock, Arkansas, 72202, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Goal-directed therapeutic protocol (a standardized care plan) and NIRS monitoring
What this could lead to
If successful, this approach could improve survival and reduce hospital stays for critically ill children with SIRS by starting treatment earlier during transport.
What could go wrong
The trial was terminated, so results are limited. It was also a small, single-center study comparing time periods, not a randomized test, making it hard to draw firm conclusions.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.