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New pill aims to slow lung scarring in IPF patients

NCT ID NCT06331624

First seen Oct 31, 2025 · Last updated May 23, 2026 · Updated 32 times

Summary

This study tested an oral drug called GRI-0621 in 35 adults with idiopathic pulmonary fibrosis (IPF), a disease that causes lung scarring and breathing problems. The main goal was to check safety and how the drug affects certain biomarkers in the blood. Participants took either the drug or a placebo daily for 12 weeks, and researchers also looked at immune cell activity in the lungs of a smaller group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Concord General Repatriation Hospital

    Concord, New South Wales, 2139, Australia

  • MUSC Pulmonary Research

    Charleston, South Carolina, 29425, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Newport Native MD, Inc.

    Newport Beach, California, 92663, United States

  • Norfolk & Norwich University Hospital

    Norwich, Norwich, United Kingdom

  • Oxford University Hospitals NHS Foundation Trust

    Oxford, OX3 7LE, United Kingdom

  • Royal Devon and University Healthcare NHS Foundation Trust

    Exeter, EX2 5DW, United Kingdom

  • Royal Infirmary Edinburgh

    Edinburgh, Scotland, EH16 4SA, United Kingdom

  • Royal Papworth Hospital NHS Foundation Trust

    Cambridge, CB2 0BB, United Kingdom

  • Southeastern Research Center

    Winston-Salem, North Carolina, 27103, United States

  • St. George Hospital

    Kogarah, New South Wales, 2217, Australia

  • The Canberra Hospital

    Garran, Australian Capital Territory, 2605, Australia

  • University College London Hospitals

    London, London, United Kingdom

  • University Hospital Birmingham, Queen Elizabeth Hospital

    Birmingham, B15 2GW, United Kingdom

  • Western Health and Social Care Trust (WHSCT)

    Londonderry, BT47 6SB, United Kingdom

Conditions

Explore the condition pages connected to this study.