New pill targets immune cells to fight lung scarring
NCT ID NCT06331624
First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 30 times
Summary
This study tested an oral drug called GRI-0621 in 35 adults with idiopathic pulmonary fibrosis (IPF), a disease that causes lung scarring and breathing problems. The drug aims to reduce scarring by blocking certain immune cells (NKT1 cells). Participants took either the drug or a placebo daily for 12 weeks. The main goals were to check safety and measure changes in biomarkers related to lung damage.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Concord General Repatriation Hospital
Concord, New South Wales, 2139, Australia
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MUSC Pulmonary Research
Charleston, South Carolina, 29425, United States
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Mayo Clinic
Jacksonville, Florida, 32224, United States
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Montefiore Medical Center
The Bronx, New York, 10467, United States
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Newport Native MD, Inc.
Newport Beach, California, 92663, United States
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Norfolk & Norwich University Hospital
Norwich, Norwich, United Kingdom
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Oxford University Hospitals NHS Foundation Trust
Oxford, OX3 7LE, United Kingdom
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Royal Devon and University Healthcare NHS Foundation Trust
Exeter, EX2 5DW, United Kingdom
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Royal Infirmary Edinburgh
Edinburgh, Scotland, EH16 4SA, United Kingdom
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Royal Papworth Hospital NHS Foundation Trust
Cambridge, CB2 0BB, United Kingdom
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Southeastern Research Center
Winston-Salem, North Carolina, 27103, United States
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St. George Hospital
Kogarah, New South Wales, 2217, Australia
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The Canberra Hospital
Garran, Australian Capital Territory, 2605, Australia
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University College London Hospitals
London, London, United Kingdom
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University Hospital Birmingham, Queen Elizabeth Hospital
Birmingham, B15 2GW, United Kingdom
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Western Health and Social Care Trust (WHSCT)
Londonderry, BT47 6SB, United Kingdom
Conditions
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